Hsp90-IN-36 (compound 5) is a Hsp90 inhibitor with anticancer activity (MCF-7, IC50=14.74 μM).

Physicochemical Properties

Molecular Formula	C20H13F4N3O4
Molecular Weight	435.33
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Design, synthesis and biological studies of new isoxazole compounds as potent Hsp90 inhibitors. Sci Rep. 2024 Nov 14;14(1):28017.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.2971 mL	11.4855 mL	22.9711 mL
	5 mM	0.4594 mL	2.2971 mL	4.5942 mL
	10 mM	0.2297 mL	1.1486 mL	2.2971 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.