Heneicosanoic acid is a long-chain saturated fatty acid that is widely found in plants and animals.

Physicochemical Properties

Molecular Formula	C21H42O2
Molecular Weight	326.56
Exact Mass	326.318
CAS #	2363-71-5
PubChem CID	16898
Appearance	White to off-white solid powder
Density	0.9±0.1 g/cm3
Boiling Point	384.3±5.0 °C at 760 mmHg
Melting Point	74-75 °C(lit.)
Flash Point	173.1±12.5 °C
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.458
LogP	9.81
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	19
Heavy Atom Count	23
Complexity	238
Defined Atom Stereocenter Count	0
InChi Key	CKDDRHZIAZRDBW-UHFFFAOYSA-N
InChi Code	InChI=1S/C21H42O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23/h2-20H2,1H3,(H,22,23)
Chemical Name	henicosanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Chemical composition of the fatty oils of the seeds of Cleome viscosa accessions. Nat Prod Commun. 2012 Oct;7(10):1363-4. [2]. Volatile oil composition of Carthamus Tinctorius L. flowers grown in Kazakhstan. Ann Agric Environ Med. 2018 Mar 14;25(1):87-89. [3]. Identification of some new minor acids from chicken skin lipids. Poult Sci. 1978 May;57(3):827-8.
Additional Infomation	Henicosanoic acid is a long-chain fatty acid that is henicosane in which one of the methyl groups has been oxidised to give the corresponding carboxylic acid. It is a straight-chain saturated fatty acid and a long-chain fatty acid. It is a conjugate acid of a henicosanoate. Heneicosanoic acid has been reported in Hoya crassipes, Hoya pseudolanceolata, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

Ethanol: 14.29 mg/mL (43.76 mM) DMSO: 3.33 mg/mL (10.20 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 1.43 mg/mL (4.38 mM) (saturation unknown) in 10% EtOH + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 14.3 mg/mL clear EtOH + stock solution to 900 μL of corn oil and mix well.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.0622 mL	15.3111 mL	30.6222 mL
	5 mM	0.6124 mL	3.0622 mL	6.1244 mL
	10 mM	0.3062 mL	1.5311 mL	3.0622 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.