HER2-targeted peptide H6F is a HER2-targeted peptide that targets breast cancer cells by binding to HER2, and its amino acid sequence is YLFFVFER. HER2-targeted peptide H6F can be coupled with the bifunctional chelator salicylamide (HYNIC) for radiolabeling with 99mTc. Single photon emission computed tomography (SPECT) imaging showed that the labeled HER2-targeted peptide H6F can specifically accumulate in the HER2-positive MDA-MBA-453 tumor mouse model. HER2-targeted peptide H6F can be used for tumor molecular imaging research.

Physicochemical Properties

Molecular Formula	C58H77N11O12
Molecular Weight	1120.30
CAS #	1644155-35-0
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	HER2
References	[1]. Development of the Tumor-Specific Antigen-Derived Synthetic Peptides as Potential Candidates for Targeting Breast and Other Possible Human Carcinomas. Molecules. 2019 Aug 29;24(17):3142.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.8926 mL	4.4631 mL	8.9262 mL
	5 mM	0.1785 mL	0.8926 mL	1.7852 mL
	10 mM	0.0893 mL	0.4463 mL	0.8926 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.