|
HDAC6-IN-32 (compound 25202) is a selective and potent HDAC6 inhibitor. HDAC6-IN-32 blocks HDAC6 activity and interferes with microtubule dynamics, leading to SAC activation and prolonged mitotic arrest, ultimately causing apoptosis in CRPC cells.
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Physicochemical Properties
| Molecular Formula |
C19H16N4O3
|
| Molecular Weight |
348.36
|
| Storage |
Powder-20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
|
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
|
Biological Activity
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Solubility Data
| Preparing Stock Solutions |
|
1 mg |
5 mg |
10 mg |
| 1 mM |
2.8706 mL |
14.3530 mL |
28.7059 mL |
| 5 mM |
0.5741 mL |
2.8706 mL |
5.7412 mL |
| 10 mM |
0.2871 mL |
1.4353 mL |
2.8706 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles. |
