Ganoderic acid D2 (compound 27) is a triterpene extracted from Ganoderma lucidum. Ganoderic acid D2 has anti-cancer, anti-inflammatory and antioxidant activities.

Physicochemical Properties

Molecular Formula	C30H42O8
Molecular Weight	530.65
Exact Mass	514.293
CAS #	97653-94-6
PubChem CID	14109398
Appearance	White to off-white solid powder
Density	1.2±0.1 g/cm3
Boiling Point	688.3±55.0 °C at 760 mmHg
Melting Point	201 - 203 °C
Flash Point	384.1±28.0 °C
Vapour Pressure	0.0±4.9 mmHg at 25°C
Index of Refraction	1.559
LogP	2.43
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Heavy Atom Count	38
Complexity	1150
Defined Atom Stereocenter Count	0
InChi Key	LCIUOVOXWPIXOR-UHFFFAOYSA-N
InChi Code	InChI=1S/C30H42O8/c1-14(10-16(31)11-15(2)26(37)38)17-12-21(34)30(7)22-18(32)13-19-27(3,4)20(33)8-9-28(19,5)23(22)24(35)25(36)29(17,30)6/h14-15,17-19,25,32,36H,8-13H2,1-7H3,(H,37,38)
Chemical Name	6-(7,12-dihydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Identification of major compounds in rat bile after oral administration of total triterpenoids of Ganoderma lucidum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2012 Apr 7;63:29-39.
Additional Infomation	7,12-Dihydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid is a triterpenoid. 7,12-Dihydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid has been reported in Ganoderma lucidum with data available.

Solubility Data

Solubility (In Vitro)

DMSO: 25 mg/mL (47.11 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 1.67 mg/mL (3.15 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 16.7 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.8845 mL	9.4224 mL	18.8448 mL
	5 mM	0.3769 mL	1.8845 mL	3.7690 mL
	10 mM	0.1884 mL	0.9422 mL	1.8845 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.