GGDPS-IN-1 (Compound 37) is a geranyl diphosphate synthase (GGDPS) inhibitor with IC50 of 49.4 nM. GGDPS-IN-1 disrupts protein geranylation in myeloma cells.

Physicochemical Properties

Molecular Formula	C15H28N4O6P2
Molecular Weight	422.35
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Geranylgeranyl Diphosphate Synthase (GGDPS)[1]
References	[1]. α-Amino bisphosphonate triazoles serve as GGDPS inhibitors. Bioorg Med Chem Lett. 2024 Feb 17:129659.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.3677 mL	11.8385 mL	23.6770 mL
	5 mM	0.4735 mL	2.3677 mL	4.7354 mL
	10 mM	0.2368 mL	1.1839 mL	2.3677 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.