Flurocitabine hydrochloride (5-Fluorocyclocytidine hydrochloride; 5'-Fluorocyclocytidine hydrochloride) is the hydrochloride form of Flurocitabine. Flurocitabine hydrochloride is hydrolyzed in vivo into two active antitumor compounds, arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU), which exert antitumor activity.

Physicochemical Properties

Molecular Formula	C9H11CLFN3O4
Molecular Weight	279.65
CAS #	40505-45-1
Related CAS #	Flurocitabine;37717-21-8
SMILES	C1=C(C(=N)N=C2N1C3C(O2)C(C(O3)CO)O)F.Cl
Synonyms	5-Fluorocyclocytidine hydrochloride; 5'-Fluorocyclocytidine hydrochloride
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Phase II study of anhydro-ara-5-fluorocytidine in adenocarcinoma of gastrointestinal tract, epidermoid carcinoma of lung, head and neck, breast carcinoma and small cell anaplastic carcinoma of lung. A study report of the E.O.R.T.C. earlyhttps://pubmed.ncbi.nlm.nih.gov/75105/.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.5759 mL	17.8795 mL	35.7590 mL
	5 mM	0.7152 mL	3.5759 mL	7.1518 mL
	10 mM	0.3576 mL	1.7879 mL	3.5759 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.