Exatecan analogue 1 (Icp-3) is an analog of Exatecan. Exatecan analogue 1 can be used to synthesize antibody-drug conjugates (ADCs).

Physicochemical Properties

Molecular Formula	C23H20FN3O4
Molecular Weight	421.42
CAS #	2671770-58-2
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Camptothecins
References	[1]. Bcma monoclonal antibody and the antibody-drug conjugate. WO2023078021 A1. 2023-05-11.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.3729 mL	11.8646 mL	23.7293 mL
	5 mM	0.4746 mL	2.3729 mL	4.7459 mL
	10 mM	0.2373 mL	1.1865 mL	2.3729 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.