(E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon present in Phlomis aurea Decne essential oil. (E)-β-Farnesene could be utilized as a feeding enhancer for the sand fly Lutzomyia longipalpis.

Physicochemical Properties

Molecular Formula	C15H24
Molecular Weight	204.35106
Exact Mass	204.188
CAS #	18794-84-8
Related CAS #	1207091-65-3
PubChem CID	5281517
Appearance	Colorless to light yellow liquid
Density	0.807 g/cm3
Boiling Point	272.5ºC at 760 mmHg
Melting Point	< 25ºC
Flash Point	230°F(110ºC)
Vapour Pressure	0.0101mmHg at 25°C
Index of Refraction	1.47
LogP	5.201
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	7
Heavy Atom Count	15
Complexity	260
Defined Atom Stereocenter Count	0
SMILES	C/C(=C/CC/C(=C/CCC(C=C)=C)/C)/C
InChi Key	JSNRRGGBADWTMC-NTCAYCPXSA-N
InChi Code	InChI=1S/C15H24/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h6,9,12H,1,4,7-8,10-11H2,2-3,5H3/b15-12+
Chemical Name	(6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Trans-beta-farnesene as a feeding stimulant for the sand fly Lutzomyia longipalpis (Diptera: Psychodidae). J Med Entomol. 1992 Mar;29(2):226-31. [2]. Chemical profiling, antiviral and antiproliferative activities of the essential oil of Phlomis aurea Decne grown in Egypt. Food Funct. 2021 May 21;12(10):4630-4643.
Additional Infomation	Trans-beta-farnesene is a beta-farnesene in which the double bond at position 6-7 has E configuration. It is the major or sole alarm pheromone in most species of aphid. It has a role as an alarm pheromone and a metabolite. beta-Farnesene has been reported in Camellia sinensis, Humulus lupulus, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

DMSO: 33.33 mg/mL (163.10 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (12.23 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.8936 mL	24.4678 mL	48.9356 mL
	5 mM	0.9787 mL	4.8936 mL	9.7871 mL
	10 mM	0.4894 mL	2.4468 mL	4.8936 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.