Diphenyl-1-pyrenylphosphine (DPPP) is a fluorescent peroxide-reactive probe. Diphenyl-1-pyrenylphosphine displays a unique AIE/ACQ transition with significant third-order nonlinear optical signal changes.

Physicochemical Properties

Molecular Formula	C28H19P
Molecular Weight	386.4242
Exact Mass	386.122
CAS #	110231-30-6
PubChem CID	130626
Appearance	Off-white to light yellow solid powder
Boiling Point	551.5±19.0 °C at 760 mmHg
Melting Point	174.0 to 178.0 °C
Flash Point	305.8±27.8 °C
Vapour Pressure	0.0±1.4 mmHg at 25°C
LogP	8.64
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	3
Heavy Atom Count	29
Complexity	527
Defined Atom Stereocenter Count	0
InChi Key	DSYGKYCYNVHCNQ-UHFFFAOYSA-N
InChi Code	InChI=1S/C28H19P/c1-3-10-23(11-4-1)29(24-12-5-2-6-13-24)26-19-17-22-15-14-20-8-7-9-21-16-18-25(26)28(22)27(20)21/h1-19H
Chemical Name	diphenyl(pyren-1-yl)phosphane
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Diphenyl-1-pyrenylphosphine: photo-triggered AIE/ACQ transition with remarkable third-order nonlinear optical signal change. Chem Commun (Camb). 2020 Apr 14;56(30):4220-4223.

Solubility Data

Solubility (In Vitro)

DMSO : ~12.5 mg/mL (~32.35 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 1.25 mg/mL (3.23 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 12.5 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.5879 mL	12.9393 mL	25.8786 mL
	5 mM	0.5176 mL	2.5879 mL	5.1757 mL
	10 mM	0.2588 mL	1.2939 mL	2.5879 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.