Dimethyl 2-oxoglutarate is a key intermediate in the Krebs cycle and an important nitrogen transporter in metabolic pathways in biological processes. The electrochemical behavior of Dimethyl 2-oxoglutarate can be studied using cyclic voltammetry, square wave voltammetry and differential pulse voltammetry using glassy carbon electrodes.

Physicochemical Properties

Molecular Formula	C7H10O5
Molecular Weight	174.15
CAS #	13192-04-6
Appearance	Liquid（1.175±0.06 g/cm3） ; Colorless to light yellow
Density	1.2±0.1 g/cm3
Boiling Point	249.4±23.0 °C at 760 mmHg
Flash Point	105.0±22.7 °C
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.427
LogP	-0.22
Synonyms	Dimethyl α-ketoglutarate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Microbial Metabolite
References	[1]. Electrochemical behaviour of dimethyl-2-oxoglutarate on glassy carbon electrodeJ. Bioelectrochemistry, 2010, 77(2): 145-150.

Solubility Data

Solubility (In Vitro)	DMSO : ~100 mg/mL (~574.22 mM; with ultrasonication)
Solubility (In Vivo)	Solubility in Formulation 1: ≥ 50 mg/mL (287.11 mM) (saturation unknown) in 0.5% CMC/saline water (add these co-solvents sequentially from left to right, and one by one), clear solution.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.7422 mL	28.7109 mL	57.4218 mL
	5 mM	1.1484 mL	5.7422 mL	11.4844 mL
	10 mM	0.5742 mL	2.8711 mL	5.7422 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.