Dihydrochlamydocin analog-1 (compound 2) is a chlamydocin analog that inhibits histone H4 peptide deacetylation with IC50 of 30 nM.

Physicochemical Properties

Molecular Formula	C28H40N4O6
Molecular Weight	528.64
CAS #	157618-75-2
SMILES	N12C(=O)C(C(c3c([H])c([H])c([H])c([H])c3[H])([H])[H])([H])N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])N([H])C(=O)C(C(C(C(C(C(C(=O)C(O[H])(C([H])([H])[H])[H])([H])[H])([H])[H])([H])[H])([H])[H])([H])[H])([H])N([H])C(=O)C1(C(C(C2([H])[H])([H])[H])([H])[H])[H]
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222. Bioorg Med Chem. 2008 Sep 15;16(18):8635-42.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.8916 mL	9.4582 mL	18.9165 mL
	5 mM	0.3783 mL	1.8916 mL	3.7833 mL
	10 mM	0.1892 mL	0.9458 mL	1.8916 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.