DM21-LG is a drug-linker conjugate for ADC that can be used to synthesize ADC molecules.

Physicochemical Properties

Molecular Formula	C60H87CLN8O18S2
Molecular Weight	1307.96
CAS #	2243689-87-2
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Abstract 2890: IMGN151 - A next generation folate receptor alpha targeting antibody drug conjugate active against tumors with low, medium and high receptor expression. Cancer Res 15 August 2020; 80 (16_Supplement): 2890.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.7645 mL	3.8227 mL	7.6455 mL
	5 mM	0.1529 mL	0.7645 mL	1.5291 mL
	10 mM	0.0765 mL	0.3823 mL	0.7645 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.