DL-O-Phosphoserine is a normal metabolite in human biological fluids and is an ester of serine and phosphate.

Physicochemical Properties

Molecular Formula	C3H8NO6P
Molecular Weight	185.07252
Exact Mass	185.009
CAS #	17885-08-4
PubChem CID	106
Appearance	White to off-white solid powder
Density	1.809g/cm3
Boiling Point	475.4ºC at 760mmHg
Melting Point	190ºC(lit.)
Flash Point	241.3ºC
LogP	-5.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Heavy Atom Count	11
Complexity	186
Defined Atom Stereocenter Count	0
InChi Key	BZQFBWGGLXLEPQ-UHFFFAOYSA-N
InChi Code	InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)
Chemical Name	2-amino-3-phosphonooxypropanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

O-phosphoserine is a serine derivative that is serine substituted at the oxygen atom by a phosphono group. It has a role as a human metabolite. It is a non-proteinogenic alpha-amino acid, a serine derivative and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonatooxyserine(2-). DL-O-Phosphoserine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). dl-O-Phosphoserine has been reported in Mycoplasma gallisepticum, Arabidopsis thaliana, and Claviceps purpurea with data available. DL-O-Phosphoserine is a metabolite found in or produced by Saccharomyces cerevisiae. The phosphoric acid ester of serine.

Solubility Data

Solubility (In Vitro)	H2O : ~25 mg/mL (~135.08 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 25 mg/mL (135.08 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.4034 mL	27.0168 mL	54.0336 mL
	5 mM	1.0807 mL	5.4034 mL	10.8067 mL
	10 mM	0.5403 mL	2.7017 mL	5.4034 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.