DHX9-IN-19 (compound 3) is an orally available DHX9 inhibitor. DHX9-IN-19 plays an important role in cancer research.

Physicochemical Properties

Molecular Formula	C20H21CLN4O4S2
Molecular Weight	480.99
CAS #	2973400-78-9
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Accent Therapeutics, Inc. Assays for monitoring inhibition of RNA helicase DHX9 by measuring the level of Alu-mediated circular RNA in relation to cancer treatment. World Intellectual Property Organization, WO2024220373 A1 2024-10-24https://patents.google.com/patent/WO2024220373A1/en?oq=WO2024220373.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.0790 mL	10.3952 mL	20.7905 mL
	5 mM	0.4158 mL	2.0790 mL	4.1581 mL
	10 mM	0.2079 mL	1.0395 mL	2.0790 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.