D-α-Aminocyclohexylacetic acid is a glycine analogue.

Physicochemical Properties

Molecular Formula	C8H15NO2
Molecular Weight	157.21
Exact Mass	157.11
CAS #	14328-52-0
PubChem CID	736849
Appearance	White to off-white solid powder
Density	1.1±0.1 g/cm3
Boiling Point	292.8±23.0 °C at 760 mmHg
Melting Point	256ºC
Flash Point	130.9±22.6 °C
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.510
LogP	1.38
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Heavy Atom Count	11
Complexity	141
Defined Atom Stereocenter Count	1
SMILES	C1CCC(CC1)[C@H](C(=O)O)N
InChi Key	WAMWSIDTKSNDCU-SSDOTTSWSA-N
InChi Code	InChI=1S/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/m1/s1
Chemical Name	(2R)-2-amino-2-cyclohexylacetic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	Commercial ergot supplements have been made from amino acids and their derivatives. They affect the release of anabolic hormones, the availability of fuel for activity, the ability to think clearly under pressure, and the prevention of muscular damage brought on by exertion. They are regarded as advantageous synergistic food ingredients [1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Solubility Data

Solubility (In Vitro)	H2O: 8.33 mg/mL (52.99 mM) H2O: 3.33 mg/mL (21.18 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 1 mg/mL (6.36 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.3609 mL	31.8046 mL	63.6092 mL
	5 mM	1.2722 mL	6.3609 mL	12.7218 mL
	10 mM	0.6361 mL	3.1805 mL	6.3609 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.