D-Valine is the enantiomer of L-Valine . L-Valine is one of twenty proteinaceous amino acid (AA)s. L-Valine is an essential amino acid (AA).

Physicochemical Properties

Molecular Formula	C5H11NO2
Molecular Weight	117.15
Exact Mass	117.078
CAS #	640-68-6
Related CAS #	L-Valine;72-18-4;D-Valine-d8;1116448-82-8
PubChem CID	71563
Appearance	White to off-white solid powder
Density	1.1±0.1 g/cm3
Boiling Point	213.6±23.0 °C at 760 mmHg
Melting Point	>295 °C (subl.)(lit.)
Flash Point	83.0±22.6 °C
Vapour Pressure	0.1±0.9 mmHg at 25°C
Index of Refraction	1.461
LogP	0.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Heavy Atom Count	8
Complexity	90.4
Defined Atom Stereocenter Count	1
SMILES	CC(C)[C@H](C(=O)O)N
InChi Key	KZSNJWFQEVHDMF-SCSAIBSYSA-N
InChi Code	InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
Chemical Name	(2R)-2-amino-3-methylbutanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Human Endogenous Metabolite
References	[1]. McCormack AL, Di Monte DA. Effects of L-dopa and other amino acids against paraquat-induced nigrostriatal degeneration. J Neurochem. 2003 Apr;85(1):82-6. [2]. Effects of D-valine on pulmonary artery endothelial cell morphology and function in cell culture. Exp Cell Res. 1984 Mar;151(1):134-47. [3]. Effects of d-valine on periodontal or peri-implant pathogens: Porphyromonas gingivalis biofilm. J Periodontol. 2018 Mar;89(3):303-314.
Additional Infomation	D-valine is the D-enantiomer of valine. It is a valine and a D-alpha-amino acid. It is a conjugate base of a D-valinium. It is a conjugate acid of a D-valinate. It is an enantiomer of a L-valine. It is a tautomer of a D-valine zwitterion.

Solubility Data

Solubility (In Vitro)	H2O: 14.29 mg/mL (121.98 mM) DMSO: < 1 mg/mL
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (853.61 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	8.5361 mL	42.6803 mL	85.3606 mL
	5 mM	1.7072 mL	8.5361 mL	17.0721 mL
	10 mM	0.8536 mL	4.2680 mL	8.5361 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.