D-methionine sulfoxide is the D-isomer of methionine sulfoxide. Methionine sulfoxide is the oxidation product of methionine. Methionine is a limiting amino acid (AA) in milk or soy protein and is easily oxidized during storage or processing.

Physicochemical Properties

Molecular Formula	C5H11NO3S
Molecular Weight	165.21
Exact Mass	165.045
CAS #	21056-56-4
Related CAS #	D-Methionine sulfoxide hydrochloride
PubChem CID	148508
Appearance	White to off-white solid powder
Density	1.4±0.1 g/cm3
Boiling Point	434.3±40.0 °C at 760 mmHg
Flash Point	216.4±27.3 °C
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.570
LogP	-1.62
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	10
Complexity	148
Defined Atom Stereocenter Count	1
SMILES	CS(=O)CC[C@H](C(=O)O)N
InChi Key	QEFRNWWLZKMPFJ-CQIZIWTCSA-N
InChi Code	InChI=1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m1/s1
Chemical Name	(2R)-2-amino-4-methylsulfinylbutanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	One of the most restrictive amino acids in poultry diets is methionine[1].
References	[1]. Availability of oxidized sulfur amino acids for the growing chick. Poult Sci. 1977 Sep;56(5):1560-5.
Additional Infomation	D-methionine S-oxide is a methionine S-oxide.

Solubility Data

Solubility (In Vitro)	H2O: 125 mg/mL (756.61 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 50 mg/mL (302.65 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.0529 mL	30.2645 mL	60.5290 mL
	5 mM	1.2106 mL	6.0529 mL	12.1058 mL
	10 mM	0.6053 mL	3.0265 mL	6.0529 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.