D-Fructose-6-phosphate disodium is an endogenous metabolite. D-Fructose-6-phosphate can be converted into D-glucose 6-phosphate by the action of phosphoglucose isomerase. D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway.

Physicochemical Properties

Molecular Formula	C6H11NA2O9P
Molecular Weight	304.10
Exact Mass	303.993
CAS #	26177-86-6
PubChem CID	22812950
Appearance	Solid powder
Boiling Point	692.5ºC at 760 mmHg
Flash Point	372.6ºC
Vapour Pressure	3.49E-22mmHg at 25°C
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Heavy Atom Count	18
Complexity	262
Defined Atom Stereocenter Count	3
SMILES	P(=O)([O-])([O-])OC([H])([H])C([H])(C([H])(C([H])(C(C([H])([H])O[H])=O)O[H])O[H])O[H].[Na+].[Na+]
InChi Key	WJTRLMLMSLDAPQ-CCXTYWFUSA-L
InChi Code	InChI=1S/C6H13O9P.2Na/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;;/h4-7,9-11H,1-2H2,(H2,12,13,14);;/q;2*+1/p-2/t4-,5-,6-;;/m1../s1
Chemical Name	disodium;[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl] phosphate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805.
Additional Infomation	D-Fructose 6-Phosphate-Disodium Salt is a phospho sugar.

Solubility Data

Solubility (In Vitro)	H2O : 100 mg/mL (328.84 mM; with sonication) DMSO : < 1 mg/mL (insoluble or slightly soluble)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (328.84 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonocation. (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.2884 mL	16.4420 mL	32.8839 mL
	5 mM	0.6577 mL	3.2884 mL	6.5768 mL
	10 mM	0.3288 mL	1.6442 mL	3.2884 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.