Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobases cytosine, pentose ribose, and a phosphate group.

Physicochemical Properties

Molecular Formula	C9H14N3O8P
Molecular Weight	323.20
Exact Mass	323.051
CAS #	63-37-6
Related CAS #	Cytidine 5′-monophosphate-15N3 disodium
PubChem CID	6131
Appearance	White to off-white solid powder
Density	2.2±0.1 g/cm3
Boiling Point	662.8±65.0 °C at 760 mmHg
Melting Point	~222 °C (dec.)
Flash Point	354.6±34.3 °C
Vapour Pressure	0.0±4.6 mmHg at 25°C
Index of Refraction	1.775
LogP	-2.03
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Heavy Atom Count	21
Complexity	531
Defined Atom Stereocenter Count	4
SMILES	C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
InChi Key	IERHLVCPSMICTF-XVFCMESISA-N
InChi Code	InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
Chemical Name	[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Human Endogenous Metabolite Microbial Metabolite
References	[1]. Hernández AG, et, al. The determination of acid-soluble nucleotides in milk by improved enzymic methods: a comparison with the ion-exchange column chromatography procedure. J Sci Food Agric. 1981 Nov;32(11):1123-31.
Additional Infomation	Cytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and a cytidine 5'-phosphate. It is a conjugate acid of a cytidine 5'-monophosphate(2-). A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase. Cytidine monophosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Cytidine-5'-monophosphate has been reported in Drosophila melanogaster, Mycoplasma gallisepticum, and other organisms with data available. Cytidine monophosphate is a metabolite found in or produced by Saccharomyces cerevisiae. Cytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. See also: Polyinosinic-polycytidylic acid (low MW) (monomer of); Polyinosinic-Polycytidylic Acid (High MW) (monomer of) ... View More ...

Solubility Data

Solubility (In Vitro)	H2O: 18.33 mg/mL (56.71 mM) DMSO: 1.1 mg/mL (3.40 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 11.11 mg/mL (34.37 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.0941 mL	15.4703 mL	30.9406 mL
	5 mM	0.6188 mL	3.0941 mL	6.1881 mL
	10 mM	0.3094 mL	1.5470 mL	3.0941 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.