Cortolone (α-Cortolone) is a metabolite of the glucocorticoid cortisol (hydrocortisone). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

Physicochemical Properties

Molecular Formula	C21H34O5
Molecular Weight	366.49
CAS #	516-42-7
Related CAS #	Cortolone-d5
SMILES	CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4(C(CO)O)O)C)O
Synonyms	α-Cortolone
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.7286 mL	13.6429 mL	27.2859 mL
	5 mM	0.5457 mL	2.7286 mL	5.4572 mL
	10 mM	0.2729 mL	1.3643 mL	2.7286 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.