Colterol is an adrenergic receptor agonist with good affinity for β1-adrenoceptor (heart) and β2-adrenoceptor (lung) with IC50 of 645 nM and 147 nM, respectively. Colterol has the potential to act as a bronchodilator.

Physicochemical Properties

Molecular Formula	C12H19NO3
Molecular Weight	225.28
CAS #	18866-78-9
Related CAS #	Colterol hydrochloride;52872-37-4;Colterol acetate;10255-14-8
SMILES	CC(NCC(C1C=CC(O)=C(O)C=1)O)(C)C
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors. Biol Pharm Bull. 1994 Aug;17(8):1023-7. [2]. Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma. Pharmacotherapy. 1985 May-Jun;5(3):127-37.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.4389 mL	22.1946 mL	44.3892 mL
	5 mM	0.8878 mL	4.4389 mL	8.8778 mL
	10 mM	0.4439 mL	2.2195 mL	4.4389 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.