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Carboxyphosphamide 22788-18-7

Carboxyphosphamide 22788-18-7

CAS No.: 22788-18-7

Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide.
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Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide.

Physicochemical Properties


Molecular Formula C7H15CL2N2O4P
Molecular Weight 293.08
CAS # 22788-18-7
SMILES

NP(N(CCCl)CCCl)(OCCC(O)=O)=O

Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenases. Biochem Pharmacol. 1988 Jul 15;37(14):2781-90.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 3.4120 mL 17.0602 mL 34.1204 mL
5 mM 0.6824 mL 3.4120 mL 6.8241 mL
10 mM 0.3412 mL 1.7060 mL 3.4120 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.