CDK2-IN-26 (compound 9) is a potent inhibitor of CDK2.

Physicochemical Properties

Molecular Formula	C20H24F2N6O5
Molecular Weight	466.44
CAS #	2821777-43-7
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	CDK2
References	[1]. Relay Therapeutics, Inc. Heterocyclic amides as CDK inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cancer. World Intellectual Property Organization, WO2023154426 A1 2023-08-17https://patents.google.com/patent/WO2023154426A1/en?oq=WO2023154426+A1.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.1439 mL	10.7195 mL	21.4390 mL
	5 mM	0.4288 mL	2.1439 mL	4.2878 mL
	10 mM	0.2144 mL	1.0719 mL	2.1439 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.