Antiviral agent 63 is a nucleoside analog with anti-HCV activity. Antiviral agent 63 can inhibit viral replication by inhibiting the activity of HCV RNA-dependent RNA polymerase or other virus-related enzymes.

Physicochemical Properties

Molecular Formula	C25H33F2N6O8P
Molecular Weight	614.54
CAS #	1613591-70-0
SMILES	C[C@]1([C@@H]([C@@](F)(COP(=O)(N[C@@H](C)C(=O)OC(C)C)OC2C=CC=CC=2)O[C@H]1N1C=NC2=C(N=C(N)N=C12)OCC)O)F
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Beigelman et al, Preparation of substituted nucleosides, nucleotides and analogs thereof as antitumor and HCV antiviral agents, WO2014100505, US, 2014-06-26.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.6272 mL	8.1362 mL	16.2723 mL
	5 mM	0.3254 mL	1.6272 mL	3.2545 mL
	10 mM	0.1627 mL	0.8136 mL	1.6272 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.