PeptideDB

Anticancer agent 197

Anticancer agent 197

CAS No.:

Anticancer agent 197 (compound 2b) is cytotoxic to HL-60 cells and A549 cells with IC50 values of 10.03 µM and 73.54 µ
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Anticancer agent 197 (compound 2b) is cytotoxic to HL-60 cells and A549 cells with IC50 values of 10.03 µM and 73.54 µM, respectively. Anticancer agent 197 can induce DNA damage.

Physicochemical Properties


Molecular Formula C22H16FENO7P
Molecular Weight 493.18
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Synthesis, anticancer activity, and molecular docking of half-sandwich iron(II) cyclopentadienyl complexes with maleimide and phosphine or phosphite ligands. Sci Rep. 2024;14(1):5634. Published 2024 Mar 7.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.0277 mL 10.1383 mL 20.2766 mL
5 mM 0.4055 mL 2.0277 mL 4.0553 mL
10 mM 0.2028 mL 1.0138 mL 2.0277 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.