Anti-NASH agent 2 (compound 21) is an anti-de novo lipogenesis activity and α-SMA gene expression inhibitor. Anti-NASH agent 2 can improve hepatic steatosis, edema, inflammatory infiltration and liver fibrosis in NASH mouse model.

Physicochemical Properties

Molecular Formula	C32H51N3O2
Molecular Weight	509.77
CAS #	3028778-28-8
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis. Bioorg Chem. 2025 Jan 7;155:108132.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.9617 mL	9.8083 mL	19.6167 mL
	5 mM	0.3923 mL	1.9617 mL	3.9233 mL
	10 mM	0.1962 mL	0.9808 mL	1.9617 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.