Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD can undergo copper-catalyzed azide-alkyne cycloaddition reaction.

Physicochemical Properties

Molecular Formula	C33H47N9O9
Molecular Weight	713.78
CAS #	2665674-77-9
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation. J Am Chem Soc. 2022 Dec 7;144(48):21831-21836.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.4010 mL	7.0050 mL	14.0099 mL
	5 mM	0.2802 mL	1.4010 mL	2.8020 mL
	10 mM	0.1401 mL	0.7005 mL	1.4010 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.