Aleuritic acid ((±)-erythro-Aleuritic acid; α-Aleuritic acid) is a major ingredient found in shellac and used in the perfumery industry as a starting material for the preparation of musk aroma. It is used as a starting material in the perfume industry for the preparation of musk aroma

Physicochemical Properties

Molecular Formula	C16H32O5
Molecular Weight	304.42228
Exact Mass	304.224
CAS #	533-87-9
PubChem CID	222178
Appearance	White to off-white solid powder
Density	1.1±0.1 g/cm3
Boiling Point	516.7±45.0 °C at 760 mmHg
Melting Point	100-101 °C(lit.)
Flash Point	280.4±25.2 °C
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.498
LogP	1.27
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	15
Heavy Atom Count	21
Complexity	245
Defined Atom Stereocenter Count	2
SMILES	C(CCC[C@H]([C@H](CCCCCCO)O)O)CCCC(=O)O
InChi Key	MEHUJCGAYMDLEL-CABCVRRESA-N
InChi Code	InChI=1S/C16H32O5/c17-13-9-5-4-7-11-15(19)14(18)10-6-2-1-3-8-12-16(20)21/h14-15,17-19H,1-13H2,(H,20,21)/t14-,15+/m1/s1
Chemical Name	(9R,10S)-9,10,16-trihydroxyhexadecanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. SUCHANDRA BISWAS. PREPARATION OF ENVIRONMENT FRIENDLY COMPOSITES FROM EFFLUENTS OF ALEURITIC ACID INDUSTRY AND MODIFIED BETEL-NUT FIBER.
Additional Infomation	Aleuritic Acid is a long-chain fatty acid.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~328.49 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (8.21 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (8.21 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (8.21 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.2849 mL	16.4247 mL	32.8494 mL
	5 mM	0.6570 mL	3.2849 mL	6.5699 mL
	10 mM	0.3285 mL	1.6425 mL	3.2849 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.