L-albizziin is a sulfhydryl reagent and a glutaminase inhibitor. L-albizziin may be used in cancer-related research.

Physicochemical Properties

Molecular Formula	C4H9N3O3
Molecular Weight	147.13
Exact Mass	147.064
CAS #	1483-07-4
PubChem CID	92891
Appearance	White to off-white solid powder
Density	1.43 g/cm3
Boiling Point	359.1ºC at 760 mmHg
Melting Point	217°C (dec.)
Flash Point	171ºC
Vapour Pressure	3.95E-06mmHg at 25°C
Index of Refraction	1.55
LogP	-4.6
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	10
Complexity	147
Defined Atom Stereocenter Count	1
SMILES	C([C@@H](C(=O)O)N)NC(=O)N
InChi Key	GZYFIMLSHBLMKF-REOHCLBHSA-N
InChi Code	InChI=1S/C4H9N3O3/c5-2(3(8)9)1-7-4(6)10/h2H,1,5H2,(H,8,9)(H3,6,7,10)/t2-/m0/s1
Chemical Name	(S)-2-amino-3-ureidopropanoic acid
Synonyms	Albizziin L-Albizziin L-AlbizziineL-beta-Ureidoalanine Albizzine NSC-132089 NSC132089NSC 132089
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	L-albizziin is a starch-based reagent that functions as an enzyme glutaminase [1].
References	[1]. Purification and characterisation of a glutaminase from Debaryomyces spp. Int J Food Microbiol. 2002;76(1-2):117-126. doi:10.1016/s0168-1605(02)00024-7.
Additional Infomation	L-Albizziine is a non-proteinogenic L-alpha-amino acid. Albizziin has been reported in Acacia paradoxa, Mariosousa millefolia, and other organisms with data available.

Solubility Data

Solubility (In Vitro)	H2O : ~50 mg/mL (~339.84 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 33.33 mg/mL (226.53 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.7967 mL	33.9836 mL	67.9671 mL
	5 mM	1.3593 mL	6.7967 mL	13.5934 mL
	10 mM	0.6797 mL	3.3984 mL	6.7967 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.