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Acridin-9-amine hydrochloride hydrate 52417-22-8

Acridin-9-amine hydrochloride hydrate 52417-22-8

CAS No.: 52417-22-8

Acridin-9-amine (9-Aminoacidine) Hydrochide Hydrate is a mutagen and DNA modifier. Acridin-9-amine Hydrochide Hydrate in
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Acridin-9-amine (9-Aminoacidine) Hydrochide Hydrate is a mutagen and DNA modifier. Acridin-9-amine Hydrochide Hydrate induces mutational damage during DNA replication.

Physicochemical Properties


Molecular Formula C13H13CLN2O
Molecular Weight 248.71
CAS # 52417-22-8
Related CAS # 9-Aminoacridine,9-Aminoacridine-13C6
Appearance Light yellow to yellow solid powder
SMILES

Cl[H].O([H])[H].N1C2=C([H])C([H])=C([H])C([H])=C2C(=C2C([H])=C([H])C([H])=C([H])C=12)N([H])[H]

Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Comparative studies of mutagenic, DNA binding and antileukaemic properties of 9-anilinoacridine derivatives and related compounds. Chem Biol Interact. 1983 Apr-May;44(1-2):53-62.

[2]. Induction of deletion and insertion mutations by 9-aminoacridine. An in vitro model. J Biol Chem. 1986 Dec 5;261(34):16226-32.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 4.0207 mL 20.1037 mL 40.2075 mL
5 mM 0.8041 mL 4.0207 mL 8.0415 mL
10 mM 0.4021 mL 2.0104 mL 4.0207 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.