Acetyl-L-lysine is an endogenously produced metabolite.

Physicochemical Properties

Molecular Formula	C8H16N2O3
Molecular Weight	188.22
Exact Mass	188.116
CAS #	1946-82-3
PubChem CID	92907
Appearance	White to off-white solid powder
Density	1.1±0.1 g/cm3
Boiling Point	438.5±40.0 °C at 760 mmHg
Melting Point	256-258 °C (dec.)(lit.)
Flash Point	219.0±27.3 °C
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.490
LogP	-1.42
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Heavy Atom Count	13
Complexity	182
Defined Atom Stereocenter Count	1
SMILES	CC(=O)N[C@@H](CCCCN)C(=O)O
InChi Key	VEYYWZRYIYDQJM-ZETCQYMHSA-N
InChi Code	InChI=1S/C8H16N2O3/c1-6(11)10-7(8(12)13)4-2-3-5-9/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
Chemical Name	(2S)-2-acetamido-6-aminohexanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

N(2)-acetyl-L-lysine is an acetyl-L-lysine where the acetyl group is located at the N(2)-posiiton. It has a role as a human metabolite. It is a tautomer of a N(2)-acetyl-L-lysine zwitterion. N-alpha-Acetyl-L-lysine has been reported in Arabidopsis thaliana, Schizosaccharomyces pombe, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

H2O :≥ 100 mg/mL (~531.29 mM) DMSO :~25 mg/mL (~132.82 mM (<60 ℃)；酸性条件溶解 (HCL 调节，pH=3) )

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (13.28 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (13.28 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (13.28 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.3129 mL	26.5647 mL	53.1293 mL
	5 mM	1.0626 mL	5.3129 mL	10.6259 mL
	10 mM	0.5313 mL	2.6565 mL	5.3129 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.