Ac-YVAD-FMK is an inhibitor of caspase 1-like protease.

Physicochemical Properties

Molecular Formula	C24H33FN4O8
Molecular Weight	524.54
CAS #	350021-87-3
SMILES	[C@@H](NC(=O)C)(C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)CF)CC1C=CC(=CC=1)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade. J Cell Biochem. 2003 Aug 1;89(5):1044-55.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.9064 mL	9.5322 mL	19.0643 mL
	5 mM	0.3813 mL	1.9064 mL	3.8129 mL
	10 mM	0.1906 mL	0.9532 mL	1.9064 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.