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Abacavir carboxylate 384380-52-3

Abacavir carboxylate 384380-52-3

CAS No.: 384380-52-3

Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor Abacavir.
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Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor Abacavir.

Physicochemical Properties


Molecular Formula C14H16N6O2
Molecular Weight 300.32
CAS # 384380-52-3
SMILES

C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)C(=O)O

Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Abacavir pharmacogenetics--from initial reports to standard of care. Pharmacotherapy. 2013 Jul;33(7):765-75. doi: 10.1002/phar.1278.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 3.3298 mL 16.6489 mL 33.2978 mL
5 mM 0.6660 mL 3.3298 mL 6.6596 mL
10 mM 0.3330 mL 1.6649 mL 3.3298 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.