ATR kinase-IN-2 (Compound IG-27) is an ATR protein kinase inhibitor with a Ki value of 0.01 ~ 1 μΜ, which can be used in tumor research.

Physicochemical Properties

Molecular Formula	C24H29F2N9O2
Molecular Weight	513.54
CAS #	1613196-91-0
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Compounds useful as inhibitors of atr kinase. WO2014089379. 2015-01-15.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.9473 mL	9.7363 mL	19.4727 mL
	5 mM	0.3895 mL	1.9473 mL	3.8945 mL
	10 mM	0.1947 mL	0.9736 mL	1.9473 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.