AMARA peptide (TFA) is a substrate of salt-induced kinase (SIK) and adenylate-activated protein kinase (AMPK).

Physicochemical Properties

Molecular Formula	C64H116F3N27O18S
Molecular Weight	1640.84
Related CAS #	AMARA peptide;163560-19-8
Appearance	White to off-white solid powder
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3. Nat Commun. 2016 Jul 27;7:12205.

Solubility Data

Solubility (In Vitro)	H2O :~50 mg/mL (~30.47 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 33.33 mg/mL (20.31 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.6094 mL	3.0472 mL	6.0944 mL
	5 mM	0.1219 mL	0.6094 mL	1.2189 mL
	10 mM	0.0609 mL	0.3047 mL	0.6094 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.