ALG-000184 is a prodrug of ALG-001075, a potent hepatitis B virus (HBV) capsid assembly modulator, and has the potential to be used in HBV infection research.

Physicochemical Properties

Molecular Formula	C23H20FN4NA2O8P
Molecular Weight	576.38
CAS #	2495324-72-4
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075. J Med Chem. 2024 Dec 12;67(23):21126-21142.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.7350 mL	8.6748 mL	17.3497 mL
	5 mM	0.3470 mL	1.7350 mL	3.4699 mL
	10 mM	0.1735 mL	0.8675 mL	1.7350 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.