ACTH (1-14) (TFA) is a bioactive peptide fragment of adrenocorticotropic hormone, which promotes the release of cortisol.

Physicochemical Properties

Molecular Formula	C79H110F3N21O22S
Molecular Weight	1794.90
Related CAS #	ACTH (1-14);25696-21-3
Appearance	Solid powder
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	Adrenocorticotropic hormone (ACTH) is a tropic hormone that is secreted by the anterior pituitary. It controls the production of androgen and cortisol and is linked to Cushing syndrome, Addison's illness, and Cushing disease[1].
References	[1]. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4.

Solubility Data

Solubility (In Vitro)	H2O :~100 mg/mL (~55.71 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 25 mg/mL (13.93 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.5571 mL	2.7857 mL	5.5713 mL
	5 mM	0.1114 mL	0.5571 mL	1.1143 mL
	10 mM	0.0557 mL	0.2786 mL	0.5571 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.