A 80426 mesylate is an α2-adrenoceptor antagonist. A 80426 mesylate can be used in antidepressant research.

Physicochemical Properties

Molecular Formula	C24H31NO5S
Molecular Weight	445.57
CAS #	152148-64-6
SMILES	CN(CCC1=CC2=C(C=C1)C=CO2)CC3CCCC4=C3C=CC=C4OC.CS(=O)(=O)O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	α2-adrenergic receptor
References	[1]. A‐80426, a potent α2‐adrenoceptor antagonist with serotonin uptake blocking activity and putative antidepressant‐like effects: I. Biochemical profileJ. Drug Development Research, 1995, 35(4): 237-245.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.2443 mL	11.2216 mL	22.4432 mL
	5 mM	0.4489 mL	2.2443 mL	4.4886 mL
	10 mM	0.2244 mL	1.1222 mL	2.2443 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.