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A274 is an extensively conjugated phenol that has recently shown to be present as a common trace constituent in randomly selected batches of commercial tissue culture media. It is a highly aromatic and mono-substituted phenol antioxidant produced during differentiation of neuroblastoma cells.
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Physicochemical Properties
| Molecular Formula |
C19H14O2
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| Molecular Weight |
274.31326
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| Exact Mass |
274.099
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| CAS # |
77273-75-7
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| Related CAS # |
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| PubChem CID |
99896
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.248g/cm3
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| Boiling Point |
410.3ºC at 760 mmHg
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| Flash Point |
184ºC
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| Index of Refraction |
1.666
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| LogP |
4.678
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
21
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| Complexity |
326
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| Defined Atom Stereocenter Count |
0
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| SMILES |
OC1=CC=C(C2C3=CC=CC=C3OC3=CC=CC=C23)C=C1
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| InChi Key |
OIXOSCRCPTVMFN-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C19H14O2/c20-14-11-9-13(10-12-14)19-15-5-1-3-7-17(15)21-18-8-4-2-6-16(18)19/h1-12,19-20H
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| Chemical Name |
4-(9H-xanthen-9-yl)phenol
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| Synonyms |
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder-20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Biological Activity
| ln Vitro |
In vitro activity:
Kinase Assay:
Cell Assay: |
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| ln Vivo |
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| Animal Protocol |
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| References |
Lipids.1981Jan;16(1):82-6.
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Solubility Data
| Solubility (In Vitro) |
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| Solubility (In Vivo) |
(Please use freshly prepared in vivo formulations for optimal results.)
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| Preparing Stock Solutions |
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1 mg |
5 mg |
10 mg |
| 1 mM |
3.6455 mL |
18.2276 mL |
36.4551 mL |
| 5 mM |
0.7291 mL |
3.6455 mL |
7.2910 mL |
| 10 mM |
0.3646 mL |
1.8228 mL |
3.6455 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles. |
