Physicochemical Properties
| Molecular Formula | C14H16N6O5 |
| Molecular Weight | 348.31 |
| CAS # | 2347524-00-7 |
| Storage |
Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition | Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs) |
Biological Activity
| ln Vitro | Azakinetin riboside (compound 7) (0-100 μM; 24, 48, 72 h) exhibits cytotoxic activity against HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, and MRC-5 cells[1]. |
| ln Vivo | Azakinetin riboside (compound 7) (0-100 μM; 24, 48, 72 h) exhibits cytotoxic activity against HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, and MRC-5 cells[1]. |
| Cell Assay |
Cell Cytotoxicity Assay[1] Cell Types: HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, MRC-5 cells Tested Tested Concentrations: 0-100 µM Incubation Duration: 24, 48, 72 h Experimental Results: Showed cytotoxic activity for HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, MRC-5 cells with IC50s of >100, 27, 25, >100, >100, >100 µM at 24 h, 14.5, 4.3, 18.7, 76, 2.8, 11.7 at 48 h, 4.6, 3.8, 11.5, 1.1, 1.1, 4.6 µM at 72 h, respectively. |
| References |
[1]. Cytotoxic effects of kinetin riboside and its selected analogues on cancer cell lines. Bioorg Med Chem Lett. 2024 Mar 1;100:129628. |
Solubility Data
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.8710 mL | 14.3550 mL | 28.7101 mL | |
| 5 mM | 0.5742 mL | 2.8710 mL | 5.7420 mL | |
| 10 mM | 0.2871 mL | 1.4355 mL | 2.8710 mL |