*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

Physicochemical Properties

Molecular Formula	C16H14CLFN4O2
Molecular Weight	348.759365558624
Exact Mass	348.078
CAS #	2252403-82-8
PubChem CID	135379087
Appearance	Typically exists as solid at room temperature
LogP	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Heavy Atom Count	24
Complexity	520
Defined Atom Stereocenter Count	0
SMILES	ClC1C(=CC2C(NC(N(C=2N=1)C1=C(C)C=CN=C1C(C)C)=O)=O)F
InChi Key	OXJTVPMAMRSGNT-UHFFFAOYSA-N
InChi Code	InChI=1S/C16H14ClFN4O2/c1-7(2)11-12(8(3)4-5-19-11)22-14-9(15(23)21-16(22)24)6-10(18)13(17)20-14/h4-7H,1-3H3,(H,21,23,24)
Chemical Name	7-chloro-6-fluoro-1-(4-methyl-2-propan-2-ylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4-dione
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Solubility Data

Solubility (In Vitro)

May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.8673 mL	14.3365 mL	28.6730 mL
	5 mM	0.5735 mL	2.8673 mL	5.7346 mL
	10 mM	0.2867 mL	1.4337 mL	2.8673 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.