6β-Hydroxy dexamethasone is the active metabolite of the synthetic glucocorticoid dexamethasone.

Physicochemical Properties

Molecular Formula	C22H29FO6
Molecular Weight	408.46
CAS #	55879-47-5
SMILES	OCC([C@]1([C@H](C)C[C@H]2[C@@H]3C[C@@H](O)C4=CC(C=C[C@]4(C)[C@@]3(F)[C@H](C[C@]12C)O)=O)O)=O
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation. J Pharmacol Exp Ther. 1996 Apr;277(1):105-12.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.4482 mL	12.2411 mL	24.4822 mL
	5 mM	0.4896 mL	2.4482 mL	4.8964 mL
	10 mM	0.2448 mL	1.2241 mL	2.4482 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.