5-Hydroxy propranolol is a metabolite of propranolol that can be used to study β-adrenergic receptor blockade.

Physicochemical Properties

Molecular Formula	C16H21NO3
Molecular Weight	275.34
CAS #	81907-82-6
Related CAS #	5-Hydroxy Propranolol-d5
SMILES	OC1C2C(=C(C=CC=2)OCC(CNC(C)C)O)C=CC=1
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Two dimensional chromatography mass spectrometry: Quantitation of chiral shifts in metabolism of propranolol in bioanalysis. J Chromatogr A. 2020 Apr 26:1617:460828.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.6319 mL	18.1594 mL	36.3187 mL
	5 mM	0.7264 mL	3.6319 mL	7.2637 mL
	10 mM	0.3632 mL	1.8159 mL	3.6319 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.