4-Methoxyphenethyl alcohol, an aromatic alcohol, is the main component of the anise-like odor produced by Amorphophallus. 4-Methoxyphenethyl alcohol can prevent E. coli from synthesizing proteins, RNA, and DNA.

Physicochemical Properties

Molecular Formula	C9H12O2
Molecular Weight	152.19
Exact Mass	152.083
CAS #	702-23-8
PubChem CID	69705
Appearance	Colorless to off-white <26°C solid; >28°C liquid
Density	1.1±0.1 g/cm3
Boiling Point	257.5±15.0 °C at 760 mmHg
Melting Point	26-28 °C(lit.)
Flash Point	110.2±14.6 °C
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.524
LogP	1.27
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Heavy Atom Count	11
Complexity	95.7
Defined Atom Stereocenter Count	0
SMILES	COC1=CC=C(C=C1)CCO
InChi Key	AUWDOZOUJWEPBA-UHFFFAOYSA-N
InChi Code	InChI=1S/C9H12O2/c1-11-9-4-2-8(3-5-9)6-7-10/h2-5,10H,6-7H2,1H3
Chemical Name	2-(4-methoxyphenyl)ethanol
Synonyms	p-Methoxyphenylethanol; 4-Methoxyphenethyl alcohol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Inhibition of protein, RNA and DNA synthesis in Escherichia coli by p-methoxyphenethyl alcohol. Biochim Biophys Acta. 1966 Sep;123(3):646-8. [2]. Inflorescence odours of Amorphophallus and Pseudodracontium (Araceae). Phytochemistry. 1997 Sep; 46(1): 71-75.
Additional Infomation	4-Methoxyphenethyl alcohol has been reported in Nymphaea rudgeana, Amorphophallus albispathus, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~657.1 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (16.43 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (16.43 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (16.43 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.5707 mL	32.8537 mL	65.7073 mL
	5 mM	1.3141 mL	6.5707 mL	13.1415 mL
	10 mM	0.6571 mL	3.2854 mL	6.5707 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.