4-Guanidinobutanoic acid is a normal metabolite present in low amounts.

Physicochemical Properties

Molecular Formula	C5H11N3O2
Molecular Weight	145.15974
Exact Mass	145.085
CAS #	463-00-3
PubChem CID	500
Appearance	White to off-white solid powder
Density	1.37g/cm3
Boiling Point	377ºC at 760mmHg
Melting Point	280-282ºC (dec.)
Flash Point	181.8ºC
Vapour Pressure	3.86E-05mmHg at 25°C
Index of Refraction	1.561
LogP	0.525
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Heavy Atom Count	10
Complexity	140
Defined Atom Stereocenter Count	0
InChi Key	TUHVEAJXIMEOSA-UHFFFAOYSA-N
InChi Code	InChI=1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)
Chemical Name	4-(diaminomethylideneamino)butanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

4-guanidinobutanoic acid is the 4-guanidino derivative of butanoic acid. It has a role as a fungal metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a butyric acid. It is a conjugate acid of a 4-guanidinobutanoate. It is a tautomer of a 4-guanidinobutanoic acid zwitterion. 4-Guanidinobutyrate has been reported in Citrus reticulata, Drosophila melanogaster, and other organisms with data available. See also: Arctium lappa Root (part of).

Solubility Data

Solubility (In Vitro)	H2O : ~25 mg/mL (~172.22 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 16.67 mg/mL (114.84 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.8890 mL	34.4448 mL	68.8895 mL
	5 mM	1.3778 mL	6.8890 mL	13.7779 mL
	10 mM	0.6889 mL	3.4445 mL	6.8890 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.