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(22R)-Budesonide 51372-29-3

(22R)-Budesonide 51372-29-3

CAS No.: 51372-29-3

(22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide. (22R)-Budesonide is a non-halogenated glucocorticoid
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This product is for research use only, not for human use. We do not sell to patients.

(22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide. (22R)-Budesonide is a non-halogenated glucocorticoid with high topical anti-inflammatory activity.

Physicochemical Properties


Molecular Formula C25H34O6
Molecular Weight 430.53
CAS # 51372-29-3
SMILES

CCCC1OC2(C(CO)=O)C(CC3C2(C)CC(O)C2C3CCC3C2(C)C=CC(=O)C=3)O1

Synonyms

(22R)-Budesonide; (22R)-BUD
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Simultaneous quantification of 22R and 22S epimers of budesonide in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry: application in a stereoselective pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15:921-922:27-34.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.3227 mL 11.6136 mL 23.2272 mL
5 mM 0.4645 mL 2.3227 mL 4.6454 mL
10 mM 0.2323 mL 1.1614 mL 2.3227 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.