2-Naphthoic acid is an organic/chemical reagent extensively used as a raw material for dyes and the production of other chemicals. It can form dyes with other organic matter and is extensively used in textiles, printing and manufacturing. In addition, the compound is also used as a photosensitive material and lubricant.

Physicochemical Properties

Molecular Formula	C11H8O2
Molecular Weight	172.18
Exact Mass	172.052
CAS #	93-09-4
PubChem CID	7123
Appearance	White to light yellow solid powder
Density	1.3±0.1 g/cm3
Boiling Point	332.9±11.0 °C at 760 mmHg
Melting Point	185-187 °C(lit.)
Flash Point	151.3±13.9 °C
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.673
LogP	3.13
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Heavy Atom Count	13
Complexity	200
Defined Atom Stereocenter Count	0
SMILES	O=C(C1C=C2C(C=CC=C2)=CC=1)O
InChi Key	UOBYKYZJUGYBDK-UHFFFAOYSA-N
InChi Code	InChI=1S/C11H8O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,12,13)
Chemical Name	naphthalene-2-carboxylic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	2-Naphthoic acid is a biochemical reagent that can be utilized in life science research as an organic compound or biological material.
Additional Infomation	2-naphthoic acid is a naphthoic acid that is naphthalene carrying a carboxy group at position 2. It has a role as a xenobiotic metabolite and a mouse metabolite. It is a conjugate acid of a 2-naphthoate.

Solubility Data

Solubility (In Vitro)

DMSO: 100 mg/mL (580.79 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (14.52 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (14.52 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.8079 mL	29.0394 mL	58.0788 mL
	5 mM	1.1616 mL	5.8079 mL	11.6158 mL
	10 mM	0.5808 mL	2.9039 mL	5.8079 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.