2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase and can be used to synthesize deoxyadenosine oligonucleotides with enzymes such as polynucleotide phosphorylase of Escherichia coli.

Physicochemical Properties

Molecular Formula	C10H13N5NA2O9P2
Molecular Weight	455.17
CAS #	72003-83-9
Appearance	White to light yellow solid powder
SMILES	P(=O)(O[H])(OP(=O)(O[H])O[H])OC([H])([H])[C@]1([H])[C@]([H])(C([H])([H])[C@]([H])(N2C([H])=NC3=C(N([H])[H])N=C([H])N=C23)O1)O[H]
Synonyms	dADP disodium
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Deutscher MP. Synthesis and degradation of poly(A) in permeable cells of Escherichia coli. J Biol Chem. 1978 Aug 25;253(16):5579-84. PMID: 353056.

Solubility Data

Solubility (In Vitro)

H2O : ~250 mg/mL (~549.25 mM; with ultrasonication)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.1970 mL	10.9849 mL	21.9698 mL
	5 mM	0.4394 mL	2.1970 mL	4.3940 mL
	10 mM	0.2197 mL	1.0985 mL	2.1970 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.