2-Aminopyrimidin-5-ol is an endogenously produced metabolite.

Physicochemical Properties

Molecular Formula	C4H5N3O
Molecular Weight	111.10
Exact Mass	111.043
CAS #	143489-45-6
PubChem CID	17750388
Appearance	Solid powder
Density	1.5±0.1 g/cm3
Boiling Point	393.6±34.0 °C at 760 mmHg
Melting Point	>170ºC (dec.)
Flash Point	191.9±25.7 °C
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.668
LogP	0.09
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Heavy Atom Count	8
Complexity	69.7
Defined Atom Stereocenter Count	0
InChi Key	NVYMOVCPYONOSF-UHFFFAOYSA-N
InChi Code	InChI=1S/C4H5N3O/c5-4-6-1-3(8)2-7-4/h1-2,8H,(H2,5,6,7)
Chemical Name	2-aminopyrimidin-5-ol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

2-Amino-5-hydroxypyrimidine is a hydroxypyrimidine.

Solubility Data

Solubility (In Vitro)

DMSO :~125 mg/mL (~1125.11 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.08 mg/mL (18.72 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	9.0009 mL	45.0045 mL	90.0090 mL
	5 mM	1.8002 mL	9.0009 mL	18.0018 mL
	10 mM	0.9001 mL	4.5005 mL	9.0009 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.